Filled with an overwhelming sense of wonder for the world around her, Mari Tamaki has always dreamt of what lies beyond the reaches of the universe. However, despite harboring such large aspirations on the inside, her fear of the unknown and anxiety over her own possible limitations have always held her back from chasing them. But now, in her second year of high school, Mari is more determined than ever to not let any more of her youth go to waste. Still, her fear continues to prevent her from taking that ambitious step forward—that is, until she has a chance encounter with a girl who has grand dreams of her own. Spurred by her mother's disappearance, Shirase Kobuchizawa has been working hard to fund her trip to Antarctica. Despite facing doubt and ridicule from virtually everyone, Shirase is determined to embark on this expedition to search for her mother in a place further than the universe itself. Inspired by Shirase's resolve, Mari jumps at the chance to join her. Soon, their efforts attract the attention of the bubbly Hinata Miyake, who is eager to stand out, and Yuzuki Shiraishi, a polite girl from a high class background. Together, they set sail toward the frozen south. Sora yori mo Tooi Basho follows the captivating journey of four spirited girls, all in search of something great.

One night, the Tokyo National Institute of Microorganisms is attacked by a mysterious organization calling themselves the "Red Siamese Cats." The group causes the explosion of a high-security lab storing a virus—said to have a mortality rate of 80% with no known cure. This act of terror dominates the headlines, overshadowing the unveiling of the world's biggest airship developed under Jirokichi Suzuki. Peculiarly, the unveiling has a note attached for Kaito "Kaitou Kid" Kuroba, challenging him to steal the jewel on display—the illustrious Lady Sky.

Conan Edogawa is permitted to board the airship along with Kogorou Mouri, Ran Mouri, Sonoko Suzuki, Professor Agasa, and the Detective Boys. However, their fun comes to a halt when an unknown caller contacts Jirokichi and declares that they have released a certain virus in the smoking room. Soon after, symptoms begin to appear among the passengers and chaos ensues. Seizing the opportunity, the Red Siamese Cats suddenly appear and hijack the airship! 

To stop the assailants, Conan and Kaitou Kid, along with their allies, must work together to decipher the clues and discover the Red Siamese Cats' real objective before time runs out.

[Written by MAL Rewrite]

In Stern Bild City, those with special abilities are called "NEXT," and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next "King of Heroes." Kotetsu T. Kaburagi, known as "Wild Tiger," is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed "Bunny" by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild. [Written by MAL Rewrite]