An artificial island in Tokyo Bay—Kyokutou Houreigai Tokubetsu Chiku (Far East Special District), commonly known as the 24-ku (24th Ward). Childhood friends Ran, Kouki, and Shuuta, who were born and raised there, have different family backgrounds, hobbies, and personalities, but always hung out together. However, their relationship changes drastically in the wake of a certain incident. At the first anniversary memorial of the incident, the three friends happen to meet again and their phones begin to ring simultaneously. The phone call is from a supposedly dead friend, urging them to "choose the future." The three will try to protect their beloved 24th Ward and the future of its people in their own ways.

This is a world where killing and torture are legalized. Sero, a part-time worker at a torture company, enjoys torturing people every day with his senior colleague, Siu. With the addition of new part-timers Mike and Hugh, fun torture life continues! The gap between the at-home, easy-going workplace and the gruesome torture is bound to attract a lot of addicts!

"Mom, I'm sorry. Please don't die." When Henry realizes death is at his mother's doorstep, he strikes a deal with a lifespan dealer to give years of his own life to his ailing mother. Now, his mother is a 20-year-old college student with a full life ahead of her, and Henry devotes his remaining days to helping her live life to the fullest. But things turn complicated when his friend falls in love with her!

The challenger has become the champion as Ippo Makunouchi now wears the featherweight championship belt of Japan. Some time has passed since Ippo's victory, and he has found his friends and coach as supportive as ever; his crush, Kumi Mashiba, seems to enjoy spending time with him as well. Things are looking bright for the new champion, but just as he once set his sights on becoming the best, his first challenger poses an intimidating threat. Kazuki Sanada works as a doctor at the same hospital as Kumi and fights strategically. Known for integrating his knowledge of the human body into his fights, Sanada is a fearsome contender—however, more unnerving than his physical ability, he has garnered the support of the nurses. Despite being the champion, Ippo feels the pressure as he must face the daunting challenge, retain his belt, and win over the girl he loves. [Written by MAL Rewrite]