Kanji Sasahara is an introverted college freshman just looking for a place to fit in. One day, he happens to stumble upon the club known as the Society for the Study of Modern Visual Culture—otherwise known as Genshiken—that serves to bring the full spectrum of otaku culture together. His first visit to the club, however, does not end well as Sasahara's pride is crushed by his senior, Harunobu Madarame, and he leaves the meeting in full denial of his otaku nature. However, after befriending club member Makoto Kousaka, who turns out to be a hardcore otaku despite his looks, Sasahara becomes more involved with club activities which include obsessing over their favorite anime, reading doujinshi, and attending conventions. There, he meets other interesting people like Kousaka's vehemently non-otaku girlfriend Saki Kasukabe, who strives to turn her boyfriend into a "normal guy." While Saki struggles to understand otaku culture and her boyfriend's love for it, Sasahara finds himself enjoying his time at Genshiken, gradually shedding any denial he once had about being an otaku and immersing himself in an otaku lifestyle. [Written by MAL Rewrite]

Perceived as strange and feared by man, over time the misshapen ones came to be known as Mushi. Although they harbor no ill intentions towards humans, many suffer from the side effects of their existence and strange nature; exploiting the Mushi without understanding them, even unintentionally, can lead to disaster and strife for any involved. Mushishi Zoku Shou continues the story of Mushishi Ginko on his journey to help the visible world to coexist with the Mushi. During his travels, Ginko discovers various gifted individuals—those cursed by circumstance and those maintaining a fragile symbiosis with the Mushi—inevitably confronting the question of whether humanity, talented and tortured alike, can manage the responsibility of the unseen. Moreover, as a Mushishi, Ginko must learn more about these strange beings and decide if he has the right to interfere with the complex relationships between Mushi and mankind. [Written by MAL Rewrite]

The fight has moved on to the next stage. A new plan is in motion... A new battle among the strongest warriors gathered across space and time has now begun!

The official website for the Nanbaka television anime announced that the "Nanfes" event in April will screen a previously unreleased anime special.