In Feudal Japan, the people of Edo are under siege by giant insects that ravage the land. The people desperately beg the government to do something about it. Thus the Insect Magistrate Office is established, gathering strong warriors to defend against the onset of pests. Mushibugyou follows Jinbee Tsukishima, a young man striving to be a master swordsman like his father. To atone for a horrific incident that occurred at his fault, Jinbee seeks to take his father's place as a member of the Insect Magistrate Office. On his journey there, he meets the lovely Haru, a young woman who helps manage her family’s tea house, and is forced to put his sword to good use in saving her from a grisly fate. This act of bravery that earns him a spot in the Insect Magistrate. Will this rookie exterminator be able to rid the land of the horde of insects swarming in?

In celebration of 20 years of , Studio Pierrot posted an anniversary PV on their YouTube channel. The PV is a compilation of newly reworked scenes from containing new animation.

The series centers on Joelle Davidovich Pomponette (Pompo-san), a talented film producer at the movie capital "Nyallywood." Despite her prowess to see through to the potential of actors and staff and bring out their talent to the fullest, she has only been producing B-class action and erotic films. One day, Pompo's "film-worm" assistant Gene, who has been doubtful of her choices of film genres, is given the task to direct a film based on a script written by her. Will Gene be able to bring Pompo's "masterpiece" to fruition?

As a spirited young girl, Yohane ventured into the big city with ambitious dreams of becoming a star. Two years later, she has yet to pass a single audition. Since Yohane cannot support herself alone, her mother invites her back home to discover something new that only she can do. With limited options and an empty wallet, Yohane reluctantly returns to Numazu, her hometown. In the seaside town, Yohane reunites with her canine companion, Lailaps, and slowly settles in, opening a fortune-telling shop. She reconnects with old friends she had forgotten and meets new ones, all of whom help in her search for a unique purpose and meaningful path in life. Unfortunately, all is not well for Yohane and the people of Numazu: a mysterious power is affecting the town and disrupting nature and wildlife. While forging stronger bonds with her newfound allies, Yohane devotes her summer to finding the magic that may help save Numazu.