Stolen from the famous "secret" Air Force base, Area 51, Lupin's most recently stolen treasure holds a secret. Four "Bloody Angels," the toughest women Lupin has ever faced, want the treasure for their own terrorist purposes. Meanwhile Zenigata teams up with a female police officer to hunt Lupin and the terrorists down.

(Source: ANN)

In the middle of an airborne heist, Lupin goes from stealing to stolen as he's carted off and forced to do a job for a mysterious man identifiable only by the brand of cigarette he smokes. Lupin's mission: to steal the infamous "Bull's Eye", a small green jewel best-known for the fact that everyone who's ever stolen it has ended up dead. Along with the challenge of alternately evading and pursuing a young thief with a competitive streak, Lupin and the gang must unravel the mystery of the Bull's Eye before its curse - or their mysterious taskmaster - gets the better of them. 

(Source: ANN)

Short specials included in the Blu-ray and DVD releases.

Dorohedoro: Ma no Omake further explores the world of sorcerers and the Hole, honing in on what the characters do in their spare time when they are not seeking out their enemies. Kamen Kakusa Fujita attends a mask conjuring ritual in hopes of a Devil bestowing him with an appropriate mask, like the ones his colleagues Noi and Shin possess. Hopefully his offering entices the mask-maker! Tenpo For You Nikaidou, lacking money and forced to sell gyoza on the streets of the Hole, stumbles upon a quaint shop selling tea and sweets. Its owner is the gentle and hospitable Syueron, but it seems the denizens of the Hole bear a grudge against him. Shitappa Seishun Graffiti Intrigued by the photographs hanging around the mansion, Ebisu approaches En hoping for a portrait of her own. However, she is disappointed to find that only members of the En Family can have their pictures taken. Anata no Shiranai Gyoza no Kai The Gyoza Fairy keeps the Hungry Bug in pristine condition, but his primary responsibility is ensuring the gyoza tastes good. So he becomes rather agitated when Nikaidou's customers do not properly enjoy their meals. Odoru Ma no Utage En is enthusiastic about his masquerade ball and is adamant on his family's participation. Per tradition, attendees must choose a partner and dance to appease the Devils. To their horror, they discover that failing to do so may incur nasty consequences! Yokaze ni Fukarete Ooba Kinenbi Nikaidou gives detailed instructions on preparing oba gyoza and Kaiman is eager to help! [Written by MAL Rewrite]