Despite a rough start, Makoto Misumi's life in another world takes a positive turn when he meets more demihumans who recognize his presence. Now as the leader of a fast-growing demihuman community, Makoto wishes to make human society more accepting of them and thus builds a business showcasing the demihumans' abilities. To extend his reach further, Makoto enrolls at the Rotsgard Academy to learn magic and expand his business venture there. Meanwhile, the goddess who summoned and forsaken Makoto had brought two other people to her world shortly after sending him away, making them heroes of their respective nations. Given enough time, Makoto's path will intertwine with both of these heroes, which may cause the world to take a drastic direction.

The Magical Kingdom of Klyrode summons hundreds of heroes from other worlds every year to fight in their war against the Dark One and his army of powerful demons. Banaza is one of those heroes, summoned from the Royal Capital Paluma, but something's not right—Banaza is only an average merchant. He has no magic, no fighting ability, and his stats are abysmal. Worse, a mishap leaves him unable to return home! Rejected as a hero and stranded in another world, abandoned to the far reaches of the kingdom by a cruel king who just wants him gone, Banaza's fate looks pretty bleak. But what will happen once the failed hero candidate finds himself with super cheat powers once he hits level two?

The introduction of 7G Network technology promised miraculous technological advancements; however, the aftermath of its launch plunged Japan into chaos. From drastic changes to the terrain to bizarre mutations among people, the way of life is overwritten with new rules. The town of Agano is one of the few remaining settlements, and its citizens aged 21 and above have transformed into animals. Shizuru Chikura, a high school student from Agano, is desperately searching for her friend, Youka Nakatomi. Coming across a picture in a newspaper placing Youka in Ikebukuro, Shizuru starts packing for a trip. But with public transportation effectively shut down, her options are limited. Fortunately, Tairo Zenjirou, a senile old conductor and the only human adult in town, comes to the rescue when he teaches her how to operate an abandoned train. With her destination set, Shizuru ventures off on a journey to find her missing friend. On the day of departure, however, her other classmates—Nadeshiko Hoshi, Reimi Kuga, and Akira Shinonome—decide to tag along at the last minute as they embark on this one-track adventure that might expose them to dangers far surpassing anything they have encountered in Agano.

When Leoleshea, a dragon god, is accidentally awoken from her sleep within a glacier, she demands this era's very best game player be brought before her. After a year of waiting, she meets Fay Theo Philus, an apostle—a human granted a supernatural ability called an Arise and thus given permission to challenge the gods in games. Fay and Leoleshea realize they share a passion for games, whether it be with cards or a battle of wits with a god. Declaring that she likes this human, Leoleshea allows Fay to call her "Leshea" and team up with her to play in the gods' games. Ever since the gods gave humans the ability to challenge them, they have promised to grant any wish after ten victories. Leshea desires to become an official god again, as she previously descended to the human world and lost her status as a divine being. Fay has only one goal: to find the woman who long ago taught him how to play games. Though Leshea and Fay quickly prove themselves to be a capable team, the gods will not allow them ten victories so easily: every game has its own unique conditions and hidden rules. Together, the duo will have to act as a perfect team to finally achieve their goals.