A young girl named Miru and Ran, a boy who appeared before Miru, embark on an adventure in an alternate world — but something tragic awaits them there...

Mami Sakura used to be a normal junior high school student, but she happened to acquire supernatural powers. Using her powers and with the help of her best friend, Mr. Takahata, she solves mysterious occurrences. When she senses someone needs help, she uses the "Teleportation Gun" and transports herself there. She then saves the world in trouble with her psychic powers, such as telekinesis and telepathy.

Aspiring samurai Shinsuke Hyoudou's world is turned upside down when he witnesses hermit Jinka Yamato and fox girl Tama Youko slay a brigands' lair in the blink of an eye. Tama happens to be katawara, a magically gifted species, who can share her powers with Jinka through a special ritual. Together, they travel the world as vigilantes to stop evil beings, be they katawara or human. As Shinsuke learns more about this new world, he discovers that monks perform inhumane research on spiritually gifted civilians, in the hope of creating human-katawara hybrids that can fight against monsters. Soon joined by Shakuyaku—a girl they manage to save from the monks’ experiments—and other allies, the group embarks on a quest to achieve their respective dreams.

Fourth season of .