Five supernatural factions have been fighting against each other for who knows how many centuries, with the beginning of Aquarian Age always in mind. Kyouta, soon begins to see visions of mystical girls fighting, except they do exist. Soon he and his girlfriend Yoriko become involved and the battle for Earth and Aquarian Age lies in their hands.

Episode 18.5: Recap Part 2, Episode 6.5.

Mister is a "coyote" or space faring outlaw who has been sitting in prison for a year for a traffic offense. Ten days from release, he breaks out with the help of his old partners Bishop and Katana. He then seeks out Franka who has been left in his care by her dead father and takes her on a journey to find her father's treasure. On their heels are the federal investigators Angelica and Chelsea as well as the android assassins of the Criminal Guild, Madame Marciano's Twelve Sisters. (Source: ANN)

Yakumo has trained and searched for 4 years, following Pai's mysterious disappearance. However, when he finally finds her, not all is well as her memory seems to be gone. They attempt to return her memory by going to the Holy Land, birthplace of the immortal race of Sanjiyans.