In the distant future, humanity has found a way to live forever by purchasing mechanical bodies, but this way to immortality is extraordinarily expensive. An impoverished boy, Tetsurou Hoshino, desires to purchase a pass on the Galaxy Express 999—a train that travels throughout the universe—because it is said that at the end of the line, those aboard can obtain a mechanical body for free. When Tetsurou's mother is gunned down by the villainous machine-man hybrid Count Mecha, however, all seems lost. Tetsurou is then saved from certain death by the mysterious Maetel, a tall woman with blonde hair and a striking resemblance to his mother. She gives him a pass to the Galaxy Express under one condition: that they travel together. Thus, Tetsurou begins his journey across the universe to many unique planets and thrilling adventures, in hopes of being able to attain that which he most desires. [Written by MAL Rewrite]

The 7th Division's Private Hyakunosuke Ogata and former Shinsengumi Vice Commander Toshizou Hijikata find themselves on opposite sides of a gang war in Barato after hearing rumors of the Hidoro gang possessing an escaped prisoner's tattooed skin. With a lead to the hidden Ainu gold close at hand, the two gladly take up arms but a betrayal will force both sides to think twice before carelessly jumping the gun.

A spin-off of featuring Sakurako and her sisters.

The Z Project was intended to give the new generation a break from caring for the old. The original intenion was to create a machine to care for them without any intervention. At first glance, it looked like an excellent plan, and many of the younger generation approved of its application. But when old Mr. Takazawa become the test subject for the Z-001 machine, Haruko questioned both the tactics of the hospital and the moral implications of the machine. This is just the beginning, as Haruko has not just the hospital, but the odds against her. But then, she discovers an odd quirk about the machine: it uses a biochip, and it eventually acquires a mind of its own!

(Source: AnimeNfo)