After living in Transylvania for several years, "Earl Dracula" (as Osamu Tezuka's official website calls him in English) has moved to Japan. In the Nerima Ward of Tokyo, he and his daughter, Chocola, and faithful servant Igor have taken up residence in an old-Western style house. While Chocola attends Junior High School, Earl Dracula is desperate to drink the blood of beautiful virgin women; an appropriate meal for a vampire of his stature. However, each night that Earl Dracula goes out on the prowl he finds himself getting involved in some kind of disturbance which leads to him causing various trouble for the local residents. With nobody in Japan believing in vampires, his very presence causes trouble amongst the people in town.

Rinka Urushiba works part time as a waitress to help out her unemployed father. By all accounts, her life in Tokyo is a relatively normal one—but her sense of normalcy begins to fade when she inexplicably sees a flying penguin one day. Chasing it all the way to the top of a building, she encounters more surprises, including flying goldfish and another person—a classmate named Kyoutarou Azuma—who can also see these strange things. After Rinka passes out when a goldfish phases through her, she wakes up an esper with the ability to phase her body through solid matter. However, her newfound ability is not the only strange thing about her: when she uses her powers, her hair turns white. Deciding reluctantly to use this new gift to help the city, she becomes Tokyo's new hero, dubbed the "White Girl." Along with Kyoutarou, who gained the power of teleportation, Rinka begins righting the wrongs in the city while fighting other espers who have much less noble intentions.

The infamous series of unexplainable murders in Hinamizawa have been solved and the chains of fate have broken due to the efforts of Rika Furude and her friends. Rika believes she has finally obtained the normal and peaceful life she desired with her friends; however, she is proven wrong when the wheels of fate begin turning once again after an unfortunate accident. Rika suddenly finds herself in a "perfect" world, the constant cycle of brutal killings having never taken place, where all of her friends are content and satisfied. Not wanting to abandon the world that she fought so hard for, she learns she must destroy an essential "key" to get back. But can Rika abandon the faultless world she is given the chance to live in, after all of her battles have brought her this far?