Bramble has always dreamed of becoming a great hero in order to gain recognition from everyone, especially his older brother, Briar. A piece of the alien nucleus that fell from the sky broke the peace of Pine Tree Mountain, but unexpectedly, Bramble merged with the alien nucleus and became a bear with alien wisdom and energy. However, this also brought about the pursuit of "alien" Abu who wanted to reclaim the nucleus.

Yui is an average schoolgirl who lives in a future where all computers are supported by a single global network known as COMNET. Yui is a computer-illiterate girl who after a computer-lab accident is approached by IR, a raccoon looking corrector computer program, which tells her she must save COMNET. She must stop the rogue A.I. (Artificial Intelligence) computer program known as Grosser and his hench-programs from taking over the world. Grosser was originally designed to be that manager of all of COMNET. At first she's very reluctant to play the heroine because of her complete lack of knowledge and ability with computers. To save COMNET she must find and gain the trust of the other seven wayward corrector programs. They must also find the creator or COMNET Professor Inukai, to help stop Grosser for good.

In the world of Mushrambo, human life has all but come to an end. After a deadly virus threatened the extinction of mankind, a new race called the Enterrans was created to preserve life on Earth. However, relations between the Enterrans and their creators did not remain peaceful. Soon a war broke out with the Enterrans fighting against the humans and their robots. Ultimately the Enterrans were the victors of this conflict, renaming Earth as Enterra in honor of their victory. Before the last vestiges of humanity fell, one of the few remaining scientists put his daughter, Yakumo Shindou, into a sleep chamber. His hope was that his daughter would one day reawaken and find the human sanctuary known as Shinzo, reviving humanity and restoring peace between humans and Enterrans. Centuries have passed since the war; Yakumo now awakens and meets an Enterran named Mashura who pledges to assist in her quest. Also joined by the Enterrans Sago and Kutal, the group must now work to locate Yakumo's missing memories and locate Shinzo. But not every Enterran is as kind as Yakumo's new friends and some are prepared to commit any atrocity to prevent the return of humanity.