At the age of 15, Hana Tabata has already made peace with the idea of never experiencing an unforgettable high school romance. Although she likes shoujo manga, flowers, and anything cute, Tabata considers herself a mere background character; she is a little bit chubby, with a round face, glasses, and freckles—all things that would make her conventionally unattractive. But when Tabata accidentally befriends Yousuke Ueno, a warm and charming classmate, things start to change. While she grapples with conflicting feelings about her unexpected new relationship with Ueno, Tabata has yet to realize that the love story she has been dreaming of has already begun.

While helping out at an anime convention to promote his city, high school student Kakeru Niimi is caught up in a sudden earthquake. During the emergency, he ends up entering a shrine where he sees a peculiar relic shatter. The very next day, his classmate Miyako Kujou, who was cosplaying at the event, worries that she has been cursed as a result of the earthquake, but Niimi brushes her suspicions off. However, Niimi's mind changes when he discovers that various people have gained supernatural powers in the city—and that some have started using them for nefarious purposes. Fortunately, Niimi is not alone: he is joined by Miyako, his sister Sora, and a cold girl named Noa Yuuki, who have all awakened to their own abilities. If the group wants to keep their hometown safe, they must strive to prevent any future incidents while unraveling the mystery behind it all.

After surviving the entrance exams, Sakuta Azusagawa has finally enrolled in the same university as his girlfriend, Mai Sakurajima. He is gradually getting used to the unfamiliar environment as he attends student gatherings and makes new acquaintances. Everything seems to be going smoothly until Sakuta's friend and Sweet Bullet idol group member Uzuki Hirokawa begins acting out. With fellow Sweet Bullet member Nodoka Toyohama pleading for his help, Sakuta realizes that he has stumbled upon another case of the inexplicable Puberty Syndrome—Uzuki is feeling pressured by the sudden surge of popularity and rumors of a potential solo career. While Sakuta searches for a solution, another occurrence of Puberty Syndrome gradually emerges from the shadows.

The all-girls Kikyo Private Academy and Chidori Public High School are polar opposites. With its prestigious history, Kikyo is attended by noble young ladies from distinguished families, while Chidori is infamously full of simple-minded delinquents. It is no surprise that their students clash with their differences. Having a tall stature and fierce appearance, Chidori student Rintarou Tsumugi is often avoided by others despite his gentle heart. One day, while helping out at his family's patisserie, he meets a customer who, after a brief moment, runs away from him. The next day, the customer returns to apologize to Rintarou, introducing herself as the cheerful Kaoruko Waguri. After spending time with Kaoruko, Rintarou appreciates that she does not judge him based on his appearance and looks forward to when they will meet again. However, when Rintarou discovers Kaoruko attends Kikyo, their relationship will challenge the social expectations and dynamics around them.