Aspiring manga artist Mizuho Nishino has grown alongside her four childhood friends: Kizuki Hazawa, Shuugo Hoshikawa, Shin Kashiwagi, and Airu Izumi. But on Mizuho's 17th birthday, Kizuki suddenly asks to be her boyfriend. Having no previous experience with romance, Mizuho brushes it off easily, but Kizuki is genuine and intends to win her heart. Kizuki no longer hides his affections, and Mizuho hesitates, worried about the consequences their potential relationship could have on their whole friend group. As Mizuho works through the confusion of youth, it seems that the other three boys have fallen for her as well—and she must find a way to sort her feelings out without shattering the close-knit group she holds dear.

Since childhood, Kazuhiro Kitase has been able to dream of a different world. He can return to reality by falling asleep or dying, and he can pick up where he left off by sleeping again. For years, he has had many adventures alongside Mariabelle, a beautiful elf who works for the Sorcery Guild. On one of their escapades, they come across the lair of a dragon taking care of its eggs. They inadvertently wake the slumbering beast, who promptly reduces them to ashes. For Kazuhiro, it is merely a temporary setback, as he can simply go back. However, he is shocked to find Mariabelle herself safe and sound asleep next to him. Kazuhiro realizes that his dream world is an alternate reality altogether. In the meantime, he makes the most of this bizarre circumstance, introducing Mariabelle to the sights and wonders of Japan. Now, with their time together spanning two worlds, their real adventures have just begun!

After contracting hepatitis A, Ezaki Yuuichi has been confined to a hospital, away from his friends and family, much to his displeasure. To relieve his boredom, he has taken to sneaking out of the hospital, usually putting himself on the receiving end of a beating from his nurse. Upon meeting a girl his age also staying in the hospital, he is immediately captivated by her beauty. Akiba Rika's personality is not quite as captivating as her beauty however. In fact, she is rather selfish, moody, and bossy. But as the two spend more time with each other, they become closer, sharing the ordinary joys and trials of a budding teenage romance, even when darkened with impending tragedy—for Rika's condition does not leave her much longer to live.

The premise of this gag manga spinoff is about three high school students: a young male student, his girlfriend and a third wheel who is a One Piece fanatic. Their names are similar to the Straw Hat Pirates and the group form a fan club dedicated to One Piece.