Nestled away on the rooftop of Tenikai General Hospital is the unconventional Department of Investigative Pathology headed by the eccentric Dr. Takao Ameku. The tiny department, consisting of Takao and her sole resident Yuu "Kotori" Takanashi, treats complex cases that most other departments within the hospital cannot resolve on their own. The mystery-obsessed Takao always tries to insert herself into cases that capture her fancy—much to the dismay of her colleagues and the police. Even if her meddling creates more problems for the hospital and those around her, none can deny the brilliance that the young department head exhibits as she weaves a diagnosis together. No matter the specialty, no case is impossible for Takao and a somewhat reluctant Takanashi to solve.

The story is set in a town where animals and vehicles live together. They cooperate to protect the townspeople from various troubles that emerge.

The young Kimball Kinnison is leaving home for a wider education when a Galactic Patrol ship crashes on his family's land and the dying pilot gives him a mysterious Lens. Half-sentient, the Lens now implanted in his hand becomes the focus of changes in Kim's life including his father's death, a space battle, and an encounter with Galactic Patrol nursing officer Chris. Impelled by the Lens, he discovers a new world of experiences opening before him and he risks his life to save Chris and the Universe. (Source: AniDB)

After years of animosity, the leaders of Osaka's Somei and Tokyo's Miyama yakuza groups have called a truce—by arranging an engagement between their respective grandchildren, Yoshino Somei and Kirishima Miyama. To this end, 17-year-old Yoshino moves to Tokyo to live with the Miyama family and attend school with her new fiancé. Although Kirishima is all smiles and perfectly polite, there is something unsettling about his demeanor that Yoshino cannot put her finger on. Yoshino's suspicions are soon confirmed: despite his manners, Kirishima is a masochistic maniac. He hurts people without batting an eye and also revels in being punished verbally and physically himself. What he wants most is a spoiled and arrogant fiancée who will ruin his life. When Yoshino does not quite meet his expectations, he reveals his true colors and openly insults her. However, instead of running away in fear, Yoshino decides to take revenge by making Kirishima fall in love with her and then ruthlessly breaking his heart.